The 9 Best Glucosamine Supplements of 2022

Glucosamine Supplement – ​​Buying Guide, Opinions and Analysis

st Glucosamine Chondroitin Msm With Optims

Glucosamine is one of the molecules responsible for keeping the cartilage that cushions the joints in good condition, coping with pressure and preventing bone friction. It is not easily obtained from food, so it is important to take a supplement to keep its levels high. One of the most recommended products is HSN HSNS-FL120, a formula that gives you 1000 mg and 120 tablets at an affordable price. Zenement Glucosamine Complex could also be the most suitable supplement, if you are looking for efficiency and quality.

The 9 Best Glucosamine Supplements – Opinions 2022

Athletes, older adults or anyone who suffers from some type of joint ailment could find the solution to the degeneration of their cartilage in glucosamine supplements. Therefore, in order to help you choose the most suitable for you, we present 9 of the best products that you can find on the market.

1. HSN Glucosamine Sulfate 1000mg

Because the main active in this formula comes from plant fermentation, this may be the best glucosamine supplement for vegans. In this way, those who follow this type of lifestyle can take care of their joints on a daily basis and prevent their deterioration.

Its concentration of 1000 mg, in each tablet, implies a sufficient amount so that the levels of this molecule remain within the recommended index, so you will only need to take one pill daily.

On the other hand, its bottle of 120 capsules is a supply for 4 months of treatment. Thus, during this period you will not have to worry about making more purchases and best of all, its cost is among the cheapest on our list. In addition, the HSN brand makes this accessory with quality raw material and EU certification, to offer confidence.

The best thing to do when purchasing any supplement is to be well informed about its characteristics. Learn more about this HSN formula.


Quantity: You do not need to purchase another container for a period of 4 months, which is practical.

Origin: Since its ingredients come from plant-based sources, it can be eaten by vegans.

Quality: In addition to the quality certifications shown by the brand, it is worth knowing that its formula is free of genetically modified organisms and allergens.


Additions: Although these are minimal servings, this supplement could be improved if anti-caking agents and silicon dioxide were removed from its ingredients.

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2. Zenement Glucosamine Complex Chondroitin MSM Boswellia and Quercetin

Zenement has combined in this product molecules such as glucosamine and chondroitin. In addition, its improved formula includes 25 mg of MSM, 30 mg of Boswellia and 5 mg of Quercetin; a set of compounds that promote regeneration and relief of joint pain, especially in the knees, back and jaw.

Contains 500 mg of glucosamine sulfate and 100 mg of chondroitin sulfate; so you can take one or two daily supplements to obtain the necessary dose. In the same way, and in order to favor its intake, it is a product presented in capsules without flavor and more digestible than tablets.

Its bottle contains 365 capsules, which gives you treatment for several months. In addition to its high-quality formula, it also offers you an affordable cost; For this reason, it is considered the best value for money glucosamine supplement at the moment.

It is a nutritional supplement that promotes the formation and repair of joint tissue. Learn a little more below.


Reliability: It is manufactured by a Spanish brand of recognized prestige and under high quality standards.

Capsules: Its flavorless capsules favor intake and are also more easily digested at the gastrointestinal level than tablets.

Efficacy: Thanks to its complete formula, it is a supplement that provides you with substances that help joint health.


Vegan: Since it is a product that contains ingredients of animal origin (crustaceans), it is not suitable for vegans.

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3. Hivital Foods Glucosamine with Chondroitin

Although glucosamine is involved in the process of keeping the body’s cartilage healthy, it is not the only substance involved. For this reason, we find options on the market combined with other supplements, such as chondroitin. In this way, it effectively contributes to preserving the elasticity and qualities of the joints.

This is precisely what the Hivital Foods brand offers you in its product. But this is not all. Also, it has been enriched with boswellia Serrata extract and quercetin, in order to reduce pain. Therefore, it is a complete supplement that attacks the main discomforts derived from the weakening of the fibers that provide mobility.

To describe its presentation, we will say that it is a bottle with 365 capsules, which will be enough for 4 months, taking the recommended dose of 3 units daily, accompanied by your food.

The best glucosamine supplement of the moment is the one with the right concentration and the qualities you are looking for. Let’s take a closer look at this product.


Combined product: It not only contributes to the health of the joints, but also to reduce the discomfort that may exist in them.

Quality: The selection of ingredients and manufacturing processes follow Spanish standards and regulations, to provide confidence in this way.

Ebook: With the purchase of the product you get, free of charge, a guide that instructs you on the correct use of this supplement.


Cost: Compared to other presentations for 4 months, the formulation has a higher price.

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4. GloryFeel Glucosamine 1,600mg with Chondroitin

Considered among the best glucosamine supplements of 2022, due to the good opinions of users, this GloryFeel brand product can be a good choice to provide a very broad beneficial effect on the body.

Its main objective is to contribute to joint health, which is why it includes chondroitin, hyaluronic acid and calcium, among other ingredients. However, we know that these substances can also make a positive change in the skin and the immune system. Therefore, the benefits are multiplied by consuming it.

In the same way, we must talk about the purity of the supplement, in general, as well as other outstanding aspects, since it is free of stabilizers, preservatives and allergens. Thus, you only get what is expected from its assets, without other alternative effects.

For offering quality at a reasonable price, GloryFeel may be the best glucosamine supplement brand. Do not forget to review our list of pros and cons that we have prepared.


Formulation: By including 4 substances that are present in the composition of the joint structures, this supplement has a broad beneficial effect on them.

Concentration: Each capsule has 800 mg of bioactive glucosamine, which is one of the highest concentrations on the market.

Convenience: It is only necessary to take 2 pills daily to cover the requirements of glucosamine.


Calcium concentration: The portion of calcium that includes the formula is only 225 mg, so it may not be enough if you experience deficiencies of this element.

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5. Doctor’s Best Glucosamine Chondroitin Msm With Optimsm 360 Capsules

Doctor’s Best is an American brand awarded with the “Good Manufacturing Practices” seal, which speaks for itself of the high quality of its products and its manufacturing processes. Thinking of improving the quality of life of people with joint problems, this manufacturer has developed this highly pure and effective nutritional supplement.

Its formula contains glucosamine sulfate from crustacean shells, chondroitin sulfate and high purity MSM. These compounds work synergistically to not only help maintain healthy joints in the body, but also to improve the overall health of skin, nails, and hair.

To optimize results, the manufacturer recommends the intake of 4 capsules daily; so you will receive a bottle containing 360 units to cover approximately 4 months of treatment.

Doctor’s Best might be the best brand for glucosamine supplements, given their experience and high quality of their products. Following is a summary of the most important aspects of this plugin.


MSM: Its formula contains high purity Methylsulfonylmethane (MSM) (99.9%), a substance that favors the formation of cartilage.

Utility: It is a recommended supplement for joint pain and to improve the health of the skin, nails and hair.

Brand: It is developed by a trusted brand and approved by the United States FDA.


Language: It is missing that the bottle label includes nutritional information and content in Spanish.

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6. SimplySupplements Glucosamine Chondroitin Vitamin C and Calcium

The main function of cartilage is to protect the bone and promote movement without pressure or friction. For this reason, it is essential to protect it and prevent its deterioration by consuming a supplement like this one offered by SimplySupplements, a product capable of providing the necessary ingredients for optimal joint health.

Its formula contains ingredients that work together, such as glucosamine and chondroitin; but in addition, it is complemented with vitamin C and calcium. For this reason, it is a supplement that gives you greater efficacy and great benefits for bone and joint health.

It should be noted that both glucosamine and chondroitin come from marine sources, which ensures greater bioavailability. Also, the recommended dose is 2 to 4 capsules; so you will receive 360 ​​supplements to cover up to 6 months of treatment.

If you are looking for an extra nutritional contribution, but you do not know which glucosamine supplement to buy, analyze the pros and cons of this product.


Ingredients: Thanks to its formula with ingredients such as glucosamine, chondroitin, calcium and vitamin C, it is a product that provides you with an effective combination to strengthen your joints.

Quantity: You will receive two bottles containing 180 capsules each; which gives you treatment for up to 6 months.

High quality: It is a supplement developed in the United Kingdom, complying with strict quality controls.


Contraindications: It is a contraindicated supplement in cases of pregnant or lactating.

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7. Solgar Glucosamine Chondroitin MSM Bones and Joints 161404

An overuse of the joints or inadequate postural and biomechanical hygiene during sports activities contribute to their deterioration and degeneration. Likewise, as our body ages, the levels of glucosamine and chondroitin tend to decrease. For this reason, if you don’t know which is the best glucosamine supplement to repair the damage done to your joints, you might want to consider this Solgar product.

It is a supplement developed with an advanced and powerful formula, which combines 1500 mg of glucosamine hydrochloride, 1200 mg of chondroitin sulfate and 700 mg of MSM; three compounds that work together to recover joint tissue. Given its level of concentration, it is a nutritional supplement that covers the recommended daily dose with a single tablet, for greater practicality. In addition, its 120 tablets offer you treatment for 4 months.

It is a product that meets the strictest quality controls, so it could be an alternative to improve your quality of life. You know its highlights.


Concentration: It is an extra concentrated supplement that gives you tablets with the necessary dose for a daily intake.

Vegan: Its formula is free of crustaceans and any substance of animal origin, making it suitable for vegans.

Gluten free: If you are intolerant to gluten, you will not have a problem with this product.


Side effects: In some people it is possible the appearance of headache at the beginning of the treatment.

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8. SimplySupplements Glucosamine Sulfate 1000 mg 120 Capsules

If you are looking among cheap supplements for one that gives you confidence and quality, you could take into account this supplement that offers you a powerful formula, with ingredients that promote the health of cartilage tissue. Therefore, it has 1000 mg of glucosamine sulfate; a substance that directly intervenes in the regenerative process of the joints.

Likewise, SimplySupplements has combined magnesium and potassium in order to provide a more complete formula. In this sense, magnesium is a nutrient that cannot be produced by the body and that promotes bone health; while potassium helps prevent osteoporosis. For this reason, the intake of these nutrients is essential for the bone system.

Similarly, given its concentration, you only need to take one capsule a day to meet the daily dose recommended by experts.

When you are looking for quality at an affordable price, this supplement could be a good option and cover your nutritional deficiencies. Continue reading for more information.


Concentration: It is a high concentration supplement, since it has a formula of 1000 mg of glucosamine sulfate.

Magnesium and potassium: It also contains magnesium and potassium; elements that favor the health of the bone system.

Quantity: You will receive a bottle containing 120 capsules, approximately for 4 months of treatment.


Combined intake: It is recommended to consult a doctor if it is possible to combine its intake with other supplements, so as not to exceed the dose of magnesium and potassium.

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9. Vegavero Glucosamine Complex Vegan & No Additives

If you are one of the people who have a vegan or vegetarian diet, this glucosamine supplement is thinking for you. Unlike other products on the market that include ingredients of animal origin. Its formula, developed in Germany by a team of nutritionists, only integrates natural plant substances that at the same time ensure greater bioavailability.

Its composition is 500 mg of naturally fermented glucosamine sulfate, 400 mg of patented vegan chondroitin sulfate, 250 mg of devil’s claw extract, 500 mg of MSM, vitamin C and zinc. All presented in capsules without gelatin and easily absorbed by the gastrointestinal system, so the body can use them more efficiently.

It is a recommended supplement to relieve joint pain and to help the health of joint tissue. In addition, its formula is free of additives, preservatives and genetically modified organisms.

It is a high-quality supplement made with plant-based ingredients, so it could be a recommended option for everyone. Next, its qualities and disadvantages.


No additives: Does not contain additives such as magnesium stearate or gelatin; it is also GMO free.

Absorption: Both glucosamine and chondroitin have been developed from plant products, which favors better absorption by the body.

Ingredients: It is a supplement that contains glucosamine, chondroitin, MSM, vitamin C, zinc and devil’s claw extract, elements that provide joint health.


Dosage: Given its low concentration, it is recommended to take three capsules a day.

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Shopping guide

This guide to buying the best glucosamine supplement is designed to let you know the most important aspects about this amino acid; vital element in the production and regeneration of joint tissue. Here you can find the parameters that you should pay attention to so that you can choose the most suitable nutritional supplement for your needs.


Glucosamine is an amino acid that is synthesized naturally from glucose and glutamine, it is also part of components such as hyaluronic acid, glycosaminoglycans and proteoglycans; essential substances for the process of cartilage tissue formation. It has a fundamental role in the formation of almost all tissues of the human body and its highest concentration is found in cartilage, joints, liver and kidney.

It plays an important role in the production of mucopolysaccharides, essential elements to repair and regenerate damaged cartilage. Likewise, it provides elasticity and increases the density of the synovial fluid; a viscous substance that improves the cushioning capacity of the joints, reducing their wear due to friction.

Likewise, glucosamine is necessary to form healthy tendons, ligaments, bones, skin and nails. It also intervenes in the formation of blood vessels and in the formation of mucous membranes in the respiratory and digestive systems. In addition, it is a compound that favors the synthesis of molecules such as glycoproteins, glycolipids and compounds such as hyaluronate.

Thanks to its properties, glucosamine offers an anti-inflammatory character that favors the progressive and consistent reduction of pain caused by degeneration in the joints. Likewise, it helps in the recovery and formation of cartilage.

Users and benefits

The function of cartilage is to cushion the impacts that occur on bone surfaces and deal with the friction that occurs with movements in the joints. By not regenerating at the required speed, the joint tissue can lose flexibility, become vulnerable and weaken when traction and compression forces are applied, either by normal daily activity or by practicing sports; in which case an early wear of the cartilage could be generated.

Joints such as ankles, knees, hips, wrists, elbows and shoulders are susceptible to injury after intense physical conditioning sessions. For this reason, athletes who perform long-term tests are the group that most frequently tends to suffer injuries to tendons, ligaments and cartilage.

This group of athletes are those who practice physical activity for long periods of time and among them we can mention speed athletes, marathoners, cyclists, long-distance runners, weight lifters, etc. In these cases, cartilage and joint injuries could become serious pathologies without proper treatment.

Similarly, people with diseases such as arthritis and osteoarthritis need extra glucosamine; since these degenerative pathologies affect the cartilage and promote the appearance of cytokines, elements that in addition to destroying also hinder its regeneration.

In this sense, the consumption of glucosamine supplements is an effective alternative that favors the elderly, people who suffer from cartilage problems and also athletes who accumulate a lot of tension in their joints. Hence the importance of knowing how to choose the most suitable product, regardless of how much it costs, since it is your health that is at stake.

Presentation and ingredients

Glucosamine is a compound available in three commercial presentations, it can come as N-acetyl glucosamine, glucosamine hydrochloride or glucosamine sulfate. Being this last presentation the best known and studied; since it has shown greater efficacy in treatments than the other two.

On the other hand, some brands include chondroitin among their ingredients, a very popular combination that provides great benefits to joint health. Likewise, there are also supplements that include MSM, vitamin C, potassium, zinc and magnesium, elements that enhance its formula.

brand and format

In the market of nutritional supplements there is a wide variety of brands, some have high quality formulations and others offer products of dubious origin, which do not meet the recommended manufacturing standards. For this reason, in your comparison of glucosamine supplements you must be attentive and bet on prestigious and recognized brands in the market.

Regarding the format, there are supplements presented in tablets, pills, capsules, creams, gel and even in sachets with a content that you can dilute in a glass of water. For this reason, regardless of whether the product is expensive or cheap, you can always find one that meets your nutritional requirements and offers easy intake.

Frequently asked questions

Q1: How to take glucosamine?

According to nutrition experts, glucosamine supplements should be taken daily in a dose not to exceed 1,500 to 2,000 milligrams. This amount can be distributed in several doses during the day, being the most recommended an intake of three daily doses. If it is the case that the presentation offers 500 mg, you could take one dose in the morning, another at noon and another at night.

However, some brands offer their supplements in a 1,000 or 1,500 mg strength, in which case you only need to take one dose per day. However, it is advisable to always follow the recommendations indicated by each manufacturer or abide by the dose that your trusted doctor indicates.

Q2: What is glucosamine with chondroitin used for?

Supplements that combine chondroitin and glucosamine are used to help keep the joints healthy in people who practice any type of exercise related to joint pressure or stress, which could cause wear and tear on this part of the body. These two substances have also shown their effectiveness in people with pathologies such as osteoarthritis and other inflammatory processes of the joints.

Glucosamine participates in the formation of cartilage tissue and in the mobility of the joints. While chondroitin, or also called chondroitin sulfate, gives cartilage elastic and mechanical properties; It is also present in connective tissues of the body.

Both glucosamine and chondroitin have been shown to be effective separately; however, when they work in synergy, they are elements that bring greater benefits to people.

Q3: What is Glucosamine Shark Cartilage good for?

Shark cartilage is a product of animal origin rich in protein, phosphorus and calcium, which could favor the protection not only of the joints, but also of the ligaments and tendons. Likewise, it helps to synthesize collagen and provide elasticity to the body’s cartilage.

However, the concentration of its active ingredient is usually too low when consumed alone; For this reason, in order to enhance its qualities, the best brands use it in combination with the beneficial properties offered by glucosamine.

On the other hand, we must not forget to mention that its natural origin and the overexploitation to which it can lead, puts the current shark population at risk, which is why environmentalists do not recommend its consumption.

Q4: Where is glucosamine extracted from?

Glucosamine is part of the synovial fluid that lubricates the joints and the cartilage components of the bones; likewise, it is present in nature. In this sense, we have that glucosamine can be obtained from the shells of shellfish or crustaceans. Likewise, various laboratories have developed research to create formulas in order to obtain this molecule from ingredients of plant origin; which could cover the requirements of the vegan public.

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